Tag Archives: Apocalypse
Inside zombie brains: Sci-fi teaches science
- A new novel “The Zombie Autopsies” is about, well, zombies
- The zombie virus basically eats the brain down to the amygdala
- When it’s humans vs. zombies, the best solution is a strategic attack, mathematician says
Zombie author and expert Dr. Steven Schlozman will join us for a Twitter chat at 12:00 p.m. ET on Tuesday, April 26. Tweet your questions to @cnnhealth and follow along at #cnnzombies.
(CNN) — An airborne virus is rapidly turning people into zombies. Two-thirds of humanity has been wiped out. Scientists desperately look for a cure, even as their own brains deteriorate and the disease robs them of what we consider life.
Relax, it’s only fiction — at least, for now. This apocalyptic scenario frames the new novel “The Zombie Autopsies” by Dr. Steven Schlozman, a child psychiatrist who holds positions at Harvard Medical School and the Massachusetts General Hospital/McLean Program in Child Psychiatry.
You might not expect someone with those credentials to take zombies seriously, but it turns out the undead are a great way to explore real-world health issues: why certain nasty diseases can destroy the brain, how global pandemics create chaos and fear, and what should be done about people infected with a highly contagious and incurable lethal illness.
“One of the things zombie novels do is they bring up all these existential concerns that happen in medicine all the time: How do you define what’s alive?” says Schlozman, who has been known to bounce between zombie fan conventions and academic meetings.
“When is it appropriate to say someone’s ‘as-good-as-dead,’ which is an awful, difficult decision?”
What a zombie virus would do to the brain
So maybe you’ve seen “Night of the Living Dead,” read “World War Z,” or can’t wait for the return of the AMC show “The Walking Dead,” but you probably don’t know what differentiates the brains of humans and zombies.
First things first: How does the zombie disease infect its victims? Many stories in the genre talk about biting, but Schlozman’s novel imagines a deliberately engineered virus whose particles can travel in the air and remain potent enough to jump from one person to another in a single sneeze.
Now, then, to the brain-eating. The zombie virus as Schlozman describes it basically gnaws the brain down to the amygdala, an almond-shaped structure responsible for the “fight or flight” response. The zombies always respond by fighting because another critical part of the brain, the ventromedial hypothalamus, which tells you when you’ve eaten enough, is broken.
The brain’s frontal lobes, responsible for problem-solving, are devoured by the virus, so zombies can’t make complex decisions. Impairment in the cerebellum means they can’t walk well, either. Also, these humanoids have an unexplained predilection for eating human flesh.
“The zombies in this book are stumbling, shambling, hungry as hell,” Schlozman said. “Basically they’re like drunk crocodiles; they’re not smart, they don’t know who you are or what you are.”
Why we love those rotting, hungry, putrid zombies
How a zombie virus would be made
So the bloodthirsty undead wander (or crawl) around spreading a lethal illness ominously called ataxic neurodegenerative satiety deficiency syndrome, or ANSD, for short.
“When something really terrifying comes along, especially in medicine or that has a medical feel to it, we always give it initials. That’s the way we distance ourselves from it,” Schlozman said.
The virus has several brain-destroying components, one of which is a “prion,” meaning a protein like the one that causes mad cow disease. In real life, prions twist when they are in an acidic environment and become dangerous, Schlozman said. How our own environment has changed to make prions infectious — getting from the soil to the cows in mad cow disease, for instance — is still a mystery.
Now here’s something to send chills up your spine: In Schlozman’s world, airborne prions can be infectious, meaning mad cow disease and similar nervous-system destroyers could theoretically spread just like the flu. Swiss and German researchers recently found that mice that had only one minute of exposure to aerosols containing prions died of mad cow disease, as reported in the journal PLoS Pathogens. A follow-up described in Journal of the American Medical Association showed the same for a related disease that’s only found in animals called scrapie. Of course, these are mice in artificially controlled conditions in a laboratory, and humans do not exhale prions, but it could have implications for safety practices nonetheless.
Like mad cow disease, the zombie disease Schlozman describes also progresses in acidic environments. In the book, a major corporation doles out implantable meters that infuse the body with chemicals to artificially lower acidity when it gets too high. But, sadly, when acidity is too low, that also induces symptoms that mimic the zombie virus, so it’s not a longterm solution. Everyone who gets exposed eventually succumbs, Schlozman said.
As for the unknown component of the zombie disease that would help slowly zombifying researchers in their quest for a cure, that’s up for the reader to figure out — and the clues are all in the book, Schlozman said.
How we’d fight back
You can’t ethically round up fellow survivors to kick some zombie butt unless the undead have technically died. And in Schlozman’s book, a group of religious leaders get together and decide that when people reach stage four of the disease, they are basically dead. That, of course, permits zombie “deanimation,” or killing.
The ‘zombie theology’ behind the walking dead
And how do you kill a zombie? Much of zombie fiction knocks out zombies through shots to the head. That, Schlozman said, is because the brain stem governs the most basic functioning: breathing and heartbeat.
A zombie-apocalypse disease like the one he describes probably wouldn’t evolve on its own in the real world, he said.
But, as we’ve seen, individual symptoms of zombies do correspond to real ailments. And if they all came together, the disease would be creepily efficient at claiming bodies, Schlozman said.
Bad news, folks: Even if people contracted a zombie virus through bites, the odds of our survival aren’t great.
A mathematician at the University of Ottawa named Robert Smith? (who uses the question mark to distinguish himself from other Robert Smiths, of course), has calculated that if one zombie were introduced to a city of 500,000 people, after about seven days, every human would either be dead or a zombie.
“We’re in big, big trouble if this ever happens,” Smith? said. “We can kill the zombies a bit, but we’re not very good at killing zombies fundamentally. What tends to happen is: The zombies just win, and the more they win, the more they keep winning” because the disease spreads so rapidly.
The best solution is a strategic attack, rather than an “every man for himself” defense scenario, he said. It would take knowledge and intelligence, neither of which zombies have, to prevail.
Why study zombies?
In his day job, Smith? models how real infectious diseases spread. But he’s already reaped benefits from his work on zombies. For instance, while many mathematical models only deal with one complicated aspect of a situation at a time, he tackled two — zombie infection and zombie-killing — when it came to speculating about outbreaks.
When it came time for modeling of real-world human papillomavirus (HPV), then, Smith? felt equipped to handle many facets of it at the same time, such as heterosexual and homosexual transmission of HPV.
“Knowing what we knew from zombies allowed us to actually take on these more complicated models without fear,” he said.
Studying zombies is also a great way to get young people excited about science. Smith?, who was on a zombie-science panel with Schlozman through the National Academy of Sciences’ Science and Entertainment Exchange in 2009, has also seen math-phobic people get interested in mathematics by reading about his work with zombies.
“There are insights that we gain from the movies, and from fiction, from fun popular culture stuff, that actually can really help us think about the way that science works, and also the way science is communicated,” he said.
And as to why people like reading about zombies and watching zombies so much, Schlozman points to the impersonal nature of things in our society, from waiting in line in the DMV to being placed on hold on a call with a health insurance company.
Think about all the situations in daily life where you sense a general lack of respect for humanity, and zombies make a little more sense.
“The zombies themselves represent a kind of commentary on modernity,” Schlozman says. “We’re increasingly disconnected. That might be the current appeal.”
THE WALKING DEAD SHOWRUNNER GLEN MAZZARA REVEALS SEASON THREE & FOUR DETAILS
Spoiler Warning: Glen Mazzara, showrunner for AMC’s The Walking Dead revealed some vital information in regards to the upcoming season of the show and mentioned that he sees the upcoming Prison arc lasting for both seasons three and four. Plus, he offers comments on pacing complaints, character evolutions/intros, the TV series catching up to the source material and more.
The Walking Dead tells the story of the months and years after a zombie apocalypse, following a group of survivors who travel in search of a safe and secure home. The series goes on to explore the challenges of life in a world overrun by walkers, where the interpersonal conflicts often present a greater danger than anything else and over time, the characters grow willing to do almost anything to survive.
As next season of The Walking Dead gears up for shooting its 16 episode order this May, fans should prepare themselves to visit the next safe haven that comic readers know all too well. During a recent round table interview, Glen Mazzara mentioned that the aforementioned Prison arc will last all of the third season until the end of season four.
“I think that a lot of people felt the farm was claustrophobic and we don’t want the prison to be that way,” said Mazzara. “The prison arc is really the heart of Robert Kirkman’s work with The Walking Dead.”
He went on to say that he plans to move closer to the source material in some aspects, but that there will of course be deviations along the way. Perhaps the largest deviation in season two was the surprise exit of Dale and therefore the lost opportunity to explore his storylines moving forward. In regards to Dale and Andrea’s love relationship, Mazzara said the writers didn’t feel the need to pursue it at all. “I don’t feel the Dale/Andrea storyline is a loss. It was never really on the table.”
One of the more intriguing comic book storylines involves Dale and group of cannibal hunters, and that will apparently live on through a different character in the TV series. “Anybody can be cannibalized, so we still have that story in the pocket.” As new characters like Michonne and the villainous Governor are introduced, I asked Mazzara if the zombies will ever take a backseat for an eventual human threat and conflict.
“Zombies will never take a backseat. We will introduce a significant human threat but the zombies are fully integrated into this world and are part of the landscape. There could be times with no zombie action but we feel we don’t need to have a 1000 zombies on the show either.”
Mazzara also confirmed that viewers can expect more ‘hero zombies’ in season three, much like the one that finished Dale off and proving Mazzara’s “quality over quantity” theory in regards to the undead. I also asked if he feels the show will catch up to the source material now that the ratings have shown continued and growing success. “Maybe we will catch up eventually; I know that Robert has no plans to end the comic.”
One of the common complaints Mazzara and the Walking Dead team have faced is purported pacing issues, which many felt caused the show to run slower in the first half before picking up later on in the season. When asked if any viewer input had an impact on this pacing change Mazzara replied, “No. My inclination was always to ramp it up after the Sophia arc and we were already so well into production that would have been impossible anyway.” Another question was asked if Mazzara’s comment of the final three episodes being a benchmark for the pacing of season three was a stab at Frank Darabont’s earlier work in which he vacated the series as showrunner after the Sophia arc. “Not at all. Frank actually wondered earlier on if we had pacing issues at the beginning himself.”
In regards to the characters, Mazzara revealed that Lori’s reaction of anger upon hearing news of Rick murdering Shane was one of shock and disgust in herself. This scene puzzled some fans when Lori implied for Rick to “deal with” Shane earlier in the season. “Lori did not ask Rick to kill Shane. She’s a confused control freak. She’s horrified at Rick and herself for her own role in this and is dealing with self hatred. She is appropriately f***ed up.”
Another character that viewers wanted to see more from was T-Dog, who many felt was underutilized. Mazzara said he was surprised by this reaction and compared T-Dog to another character by the name of Ronnie from Mazzara’s writing days on The Shield. He did however admit that they might have went a bit far in ignoring him to some degree saying, “He has been off to the side and forgotten so we’re going to correct this now that he’s survived the finale and develop him from being a background character in significant ways.”
As for new characters, he went on to confirm the sword-wielding Michonne (Danai Gurira) will have a vital role and said that, although her surprise entrance in season two was very “theatrical”, he does want to ground that character and make her real and gritty. The Governor, played by David Morrissey, is a good friend of Andrew Lincoln (who plays Rick) in real life. Mazzara mentioned that although he was not familiar with Morrissey’s work, Lincoln’s praise along with Morrissey’s audition were perfect. The actor understood that the Governor’s essence is that of a true villain.
Other interesting notes include
- Mazzara confirmed fan favorite Merle (Michael Rooker) is “on the horizon” for season three.
- Greg Nicotero will shoot webisodes based on different characters sometime next month.
- Horror novelist Stephen King will not direct an episode of the series as he was Darabont’s connection.
- The bar shoot-out in the episode ‘Triggerfinger’ was inspired by a similar scene from HBO’s The Wire.
- A writer from HBO’s The Sopranos has been added to the TWD team.
- Security has been ramped up significantly to prevent leaks, which were a huge plague for season two.
- Scripts for season three are being written simultaneously in a style that Frank Darabont introduced that he learned while working with George Lucas. Mazzara will write the third season premiere.
- Despite the prison arc showcasing some of the darkest aspects of the series, Mazzara confirmed that there’s“no place they won’t go” in those terms although they may utilize off-screen effects in some situations.
- Mazzara’s friend Kurt Sutter (creator of Sons of Anarchy) will likely have a zombie cameo next season while Mazzara plays a dead biker on SOA to seal the deal. “I love Kurt, so I might take him up on that offer.”
Soviet Expiriment resurected dead, Real Zombies
In the 1940s, Soviet scientists were able to bring the dead back to life. This very technology will be the driving force behind the future Zombie apocalypse. 71 years later, we can finally get a peek through the Iron Curtain. What you see might horrify you. A poor dog, Torn apart in the name of science. Its lungs, hart and head, put to death then reanimated. Was this ever tested on humans, are Zombies real? Yes, as we can see, this has been done a very long time ago. Deep within Soviet Russia the communists scientist have played God. The day of Judgement will rain down on humanity and the dead shall rise. Nazi also conducted experiments with for nazi zombies. refer to times article for more details